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Total mortality (TM) was also considered as an end point and 37 deaths were recorded (arrhythmic = 13, pump failure = 17, non cardiac = 7). LVEF, filtered QRS (SAECG), NSVT > 1/24 hours, VPBs > 240/24 hours, Decelaration http://en.wikipedia.org/wiki/Resveratrol Capacity (DC) of heart rate, mean Heart Rate (HR), SDNN/HRV, QTc and the scale dependent wavelet- coefficient standard deviation [��wav (m)] of multiresolution wavelet analysis (MWA �C Haar 8) of HRV were calculated and statistically analyzed for the two groups. Results:��wav (m) was a statistically significant predictor of SCD (Long rank test p = 0.0006). After Cox regression analysis adjusted for LVEF, gender, fQRS, NSVT episodes >1/24hours, VPBs > 240/24 hours, DC, HR, and SDNN, the ��wav (m) remained an important and independent SCD predictor with HR:0.991 (P http://www.selleckchem.com/products/Aloxistatin.html failure pts cohort with a short term follow up, ��wav (m) was an important and independent predictor both for SCD and TM. P159 PROGRAMMED VENTRICULAR STIMULATI- ON AS COMPARED TO THE NON INVASIVE RISK STRATIFIERS FOR SUDDEN CARDIAC DEATH PREDICTION AMONG SEVERE HEART FAILURE PATIENTS Gatzoulis K; http://www.selleckchem.com/products/DMXAA(ASA404).html Arsenos P; Dilaveris P; Gialernios T; Kartsagoulis E; Sideris S; Archontakis S; Tsiachris D; Aggelis A; Stefanadis C; APRET First Department of Cardiology, Medical School, National & Kapodistrian University of Athens, Greece Purpose: To examine the prediction ability of VT/VF inducibility on Programmed Ventricular Stimulation (PVS) for Sudden Cardiac Death (SCD) among Heart failure (HF) patients (pts). Methods: We screened 114 HF pts (age: 67 �� 11 years, male: 83%, LVEF: 29 �� 9.5, NYHA: 2.4 �� 0.5, CAD: 72%, DCMP: 28%) under optimum treatment with ECG, SAECG, ECHO and 24 hour HOLTER. All pts underwent also a PVS. After 14.1 �� 12.6 months of follow up the sample divided to the HIGH risk (24 pts) and the LOW risk (90 pts) groups according to three SCD events/surrogates: 1. clinical VT/VF 2. ICD's appropriate activation 3. confirmed SCD. Data calculated and statistically analyzed for the two groups. Results: ? HIGH RISK LOW RISK p ? (n = 24) (n = 90) value LVEF (%) 27.9 �� 9.5 ?30.3 �� 10.0 0.2 QRS (ms) 120 �� 33 125 �� 32 0.6 FQRS (ms) 146 �� 29 146 �� 30 0.9 QTc (ms) 471 �� 51 469 �� 57 0.9 Heart Rate 69.7 �� 9? 69.9 �� 9? 0.9 NSVT (episodes nb) ?4.2 �� 7.7 ??22.2 �� 107.3 0.4 VPBs (nb) ?1483 �� 3355 ?2437 �� 4139 0.3 VT/VF on PVS (nb/%) 18 (75%) 46 (51%) ?0.03 After multiple logistic regression analysis adjusted for male, age, LVEF, and VT/VF on PVS the only independent and important SCD predictor was VT/VF inducibility on PVS with OR: 3.101 (p = 0.03, 95%CI: 1.101�C8.731).
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