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This study evaluated the relationships between the clinical features of adenocarcinoma of the large bowel, the histopathologic subtypes, and treatment. Patients with adenocarcinoma of the large bowel presenting to the Korle Bu Teaching Hospital from January 1997 to December 2011 were studied. The study involved 579 patients: 310 (53.5%) males and 269 (46.5%) females, median age 58 years. Right colon cancers were 170 (29.4%), left colon 128 (22.1%), and rectum 281 (48.5%). Well-differentiated cancers were 254 (43.3%), moderately differentiated 178 (30.3%), mucinous 90 (14.8%), anaplastic 44 (7.5%), and signet-ring cell cancer 13 (2.2%). The mean ages across the histologic types were unequal, F-test 8.34, P-value 0.0005, with patients with mucinous and signet-ring cancers http://www.selleck.cn/products/Staurosporine.html much younger. Mucinous cancers were predominantly in the right colon while signet-ring cell http://www.selleckchem.com/products/ly2109761.html cancers were mostly in the rectum. Well- and moderately differentiated cancers presented at early stage than anaplastic and signet-ring cell cancers, P???0.01 and P? http://www.selleckchem.com/products/epz-5676.html identified with the PT injection (range: 1�C4, P?