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3, 6.3 and 13.5%, respectively. Survival curves after liver transplantation, in relationship to the median HCC-MELD value, are reported in Figure 2. Patients with an HCC-MELD score below http://www.selleck.cn/products/azd9291.html 9.3% had 1-, 3- and 5-year survival rates of 91.3, 87.4 and 80.5%, respectively, whereas patients with an HCC-MELD score �� 9.3% had significantly lower survival rates of 84.0, 69.0 and 63.3%; respectively (Figure 2A; p = 0.001). The 1-, 3- and 5-year HCC recurrence rates of patients with lower HCC-MELD scores were 2.1, 5.3 and 7.5%, respectively and of patients with higher HCC-MELD scores were 9.3, 17.0 and 19.1%, respectively (Figure 2B; p = 0.002). Table 2 reports univariate Cox regression analysis on patient survival after transplant. Preoperative variables found to be significantly related to survival were female recipient gender (p = 0.036); HCV positivity (p = 0.002); http://www.selleckchem.com/products/Gemcitabine-Hydrochloride(Gemzar).html serum AFP (p http://www.selleckchem.com/products/birinapant-tl32711.html of MVI was also similar (54.4% in HCV positive and 51.6% in HCV-negative patients; p = 0.694). The baseline 5-year survival of the whole study population, at mean of covariates, was 76.9% with a ��-coefficient for the HCC-MELD score of 2.62. Stratifying Cox regression for HCV serology status, the baseline 5-year survival for HCV-negative patients was 83.7% and for HCV-positive patients it was 70.6% when adjusted for cold ischemic time. Relationships observed between the HCC-MELD score and the 5-year predicted survival after transplantation are reported in Figure 3A; the higher the probability of dropout while on the waiting list, the lower the predicted survival after transplantation, that is worsened by HCV-positivity.