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punctatus and is shown in Table 3. Within the body albumin and globulin makes most of the proteins and alteration in the quantities of these proteins occur due to which the A:G ratio gets disturbed when intoxicated with xenobiotics/heavy metals. In the present study significant increase was observed in the serum http://www.selleckchem.com/products/LDE225(NVP-LDE225).html total protein. Albumin level fall significantly (p? http://en.wikipedia.org/wiki/Levetiracetam is an index used to track changes in the composition of serum or plasma ( Mazeoud et al., 1977) and its normal value lies between 0.8 and 2.0, reported for mammalian models. In the present study the ratio of A:G was less than 0.8 in serum and muscle of exposed fish. However in liver of exposed fish the A:G ratio was 1.13 which was higher than 0.8 but below 2.0. Since albumin is entirely produced by the liver so an increase in albumin and total protein in the present study could be attributed toward the protein synthesis for utilization to meet high energy demand. The low albumin level than globulin in all the cases including the present case (excluding liver) could be ascribed as the utilization of albumin to meet the immediate energy demand hence rapid synthesis takes place in the liver, and higher globulin levels to meet the immunotoxic challenges. It is also said that the fishes which have low levels of globulins were less likely to survive in polluted waters because it impart immune resistance. Moreover the increased protein levels in the liver could also be due to the effort of liver to repair their damaged tissues as a result low levels were reported in serum despite synthesis. Therefore estimation of total protein alone to check health status of fish would be misguiding. After all necrosis of hepatic tissue was more likely the cause of the disturbance of protein constituents in Thermal Power Plant effluent exposed fish C. punctatus. Serum lipid profile of both the samples of C. punctatus is shown in Table 4.