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For this reason, the models were estimated among those whose grafts survived for at least 1 year (models estimated among 2- and 3-year survivors yielded similar results). Focusing on 1-year survivors also removes possible bias from differential rates of acute rejection between AA and non-AA patients that occur in the months after transplantation that were not related to the expiration of drug coverage. We then estimated a Cox proportional hazard regression to determine the impact of lifetime coverage on income disparities in graft survival among AA transplant recipients while controlling for potential http://www.selleckchem.com/products/pf-562271.html confounding recipient, donor and transplant characteristics listed in Table 1. Risk ratios were estimated for variables representing the lowest zip code income quartile (income quartile 1), eligibility based on age or disability status (aged/disabled), http://www.selleckchem.com/products/VX-765.html eligibility based on receiving a transplant after January 1, 1997 (Post 1997), the two-way interactions between low income, eligible for coverage based on age or disability status and transplanted after January 1, 1997 and a three-way interaction term to capture the statistical effect of the presence of all three factors (low income, eligible for coverage based on age or disability status and transplanted after January 1, 1997). As in the previous exercise, the hazard ratio for three-way interaction estimated the incremental effect of the extended lifetime coverage to low-income AA patients whose age or disability status qualified them to receive it. The model included these seven variables and those confounding recipient, donor and transplant factors found to be significant at p http://www.selleck.cn/products/azd6738.html donor transplant recipients, 8003 were identified as AA patients with the remaining 16 587 identified as non-AA patients. Descriptive statistics for AA and non-AA patients are reported in Tables 1 and 2, separated by eligibility criteria (over age 65 or disabled) and time period of transplantation (before and after January 1, 1997). Before the coverage extension, 5-year graft survival for eligible (over age 65 or disabled) AA patients was 50.65%, compared to 59.76% among non-AA patients (Panel A of Figure 1; p