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70). Conclusions:? The BFSQ is a psychometrically sound self-report measure that can be used to effectively quantify functional status across different clinical states in patients with bipolar disorder. ""Marsh WK, Ketter TA, Crawford SL, Johnson JV, Kroll-Desrosiers AR, Rothschild AJ. Progression of female reproductive stages associated with bipolar illness exacerbation. Bipolar Disord 2012: 14: 515�C526. ? 2012 The Authors. Journal compilation ? 2012 John Wiley & Sons A/S. Objectives:? Late perimenopause and early http://www.selleckchem.com/products/abt-199.html postmenopause confer an increased risk of depression in the population, yet bipolar disorder mood course during these times remains unclear. Methods:? Clinic visits in 519 premenopausal, 116 perimenopausal (including 13 women transitioning from perimenopause to postmenopause), and 133 postmenopausal women with bipolar disorder who received naturalistic treatment in the multisite Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study over 19.8?��?15.5?months were analyzed for mood state. History of postpartum and perimenstrual mood exacerbation and current hormone therapy were evaluated as potential mood predictors. Results:? A progression in female reproductive stage (premenopause, perimenopause, http://www.selleck.cn/products/CP-690550.html and postmenopause) was significantly associated with percent of visits decreasing in euthymia (29.3%, 27.0%, 25.0%, respectively, p? http://www.selleckchem.com/products/ABT-263.html therapy did not significantly alter depression during perimenopause. Conclusions:? A progression in female reproductive stages was associated with bipolar illness exacerbation. A small number of women transitioning from perimenopause to postmenopause had significantly greater depression than other female reproductive groups. Euthymia and mood elevation decreased with progressing female reproductive stage. Menstrual cycle or postpartum mood exacerbation, or current hormone therapy use, was not associated with perimenopausal depression. Future studies, which include hormonal assessments, are needed to confirm these preliminary findings. ""Sheeran T, Greenberg RL, Davan LA, Dealy JA, Young RC, Bruce ML. A descriptive study of older bipolar disorder residents living in New York City��s adult congregate facilities. Bipolar Disord 2012: 14: 756�C763. ? 2012 John Wiley & Sons A/S.