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With regard to the effects of HMAs, decitabine showed a trend of better survival than azacitidine in patients http://www.selleckchem.com/products/Vorinostat-saha.html significant. In the propensity score-matched cohort, we also stratified analyses according to age at HMA initiation. In patients http://www.selleck.cn/products/ve-821.html of treatment, deaths occurred in 10 (5%) of the 203 patients in the azacitidine group and 8 (8%) of the 97 patients in the decitabine group. These deaths were attributable to sepsis after 1 or 2 cycles of HMA, with the exception of 1 patient with a life-threatening brain haemorrhage. Grade 3 or 4 neutropenia was more common in the decitabine group (87%) than in the azacitidine group (67%). The number of infectious episodes treated with intravenous antimicrobials was significantly lower in the azacitidine group (11��8 per 100 cycles) than in the decitabine group (15��7 per 100 cycles) (relative risk 0��75; 95% CI 0��58�C0��96; P?=?0��02). In the propensity score-matched cohort, the higher incidence of grade 3 or 4 cytopeniain the decitabine group was http://www.selleckchem.com/products/Cisplatin.html unchanged. Susceptibility to infection was shown to be more prominent in the decitabine group (relative risk 0��55; 95% CI 0��40�C0��76; P?