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In this study, we performed a retrospective investigation of these aspects, and considered its roles. Between January 2008 and December 2010, 73 living donor liver transplantations were performed in our department. Twenty seven courses of apheresis and dialysis were performed http://en.wikipedia.org/wiki/MYO10 for 19 of those patients (19/73; 26.0%). The indications were ABO incompatible-liver transplantation in 11 courses, fluid management in seven, acute liver failure in three, renal replacement therapy in two, endotoxin removal in two, cytokine removal in one, and liver allograft dysfunction in one. Sixteen courses of apheresis and dialysis were performed prior to liver transplantation for 14 patients. The median IgM antibody titers before and after apheresis for ABO blood type-incompatible liver transplantation was 128 and eight, respectively (P? http://www.selleckchem.com/products/poziotinib-hm781-36b.html patients was 100%. Apheresis and dialysis in pediatric living donor liver transplantation are effective for antibody removal in ABO-incompatible http://www.selleckchem.com/products/bay80-6946.html liver transplantation, and fluid management for acute respiratory failure. Liver transplantation (LT) has become a standard treatment for patients with end-stage liver disease, and there is a controversy related to the role of apheresis and dialysis in the perioperative management of LT. Although apheresis and dialysis may play a significant role in the perioperative management of these patients, acute renal failure (ARF) in either pre or post-liver transplant is not an established indication for apheresis. Fluid management is an indication for dialysis, but this is truly not an apheresis technique. Not only standard apheresis (i.e. plasma exchange [PE]), but also selective extracorporeal apheresis technology, such as continuous hemodiafiltration (CHDF), direct hemoperfusion with a polymyxin B-immobilized fiber column (PMX-DHP), and double filtration plasmapheresis (DFPP) are used for elimination of endotoxin, cytokines, or antibodies, etc. Therefore, the indications for apheresis and dialysis, and its efficacy and safety in pediatric liver transplant recipients are still a matter of debate. In the field of LT, the indications for apheresis and dialysis are classified as renal indications and non-renal indications.