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Given that average effects across a group may not be meaningful to the individual child, reference values are required to determine whether changes in score on a measure of an individual child has achieved a real improvement or is only because of random measurement error (Flansbjer et?al. 2005). The MDC is such a reference http://www.selleckchem.com/products/dabrafenib-gsk2118436.html that determines the importance of changes in making the decisions to modify the child's therapy programme accordingly. We found that the MDCs of the three measures were http://www.selleck.cn/products/z-vad-fmk.html (Kovacs et?al. 2008), sensitivity and specificity associated with these potential cut-off scores could be valuable in the decision-making process as well. Because the area under http://www.selleckchem.com/products/sch772984.html ROC curves for these three measures only indicated fairly acceptable discriminative ability, in-depth clinical observations and interviews should be supplemented while administering these measures to children with ID. Regard to the feasibility of these three measures, the averaged administering times for the BOT-2, MABC-2 and PDMS-2 were 97, 47 and 71?min respectively. To successfully administer the test to the population, all three measures use toy-like materials and goal-directed activities that are age-appropriate and appeal to the children. These measures also place minimal demands on other skills that may reduce the child's motor performance, such as cognition, perception and language. As regards to the burden of the user, the BOT-2 has a more complicated scoring system and items than the MABC-2 and the PDMS-2 (Wuang et?al. 2009). Although the PDMS-2 also has plenty of test items, the examiner could choose the item close to the child's developmental level as an entry point for administering instead of conducting all items.