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4% in men and 46.9% in women. OAB was associated with significant impairments across all domains of patient-reported outcomes, including general HRQL (Medical Outcomes Study 12-item Short-Form Survey), ratings of anxiety and depression (Hospital Anxiety and Depression Scale), and urinary condition�Cspecific outcomes (Overactive Bladder Questionnaire Short Form and Patient Perception of Bladder Condition) (P http://www.selleckchem.com/products/BEZ235.html are low. Older patients should be assessed for OAB. ""OBJECTIVES: To describe associations between dietary nutrient intake and progression of sarcopenia, the age-related loss of muscle mass and strength. DESIGN: Prospective cohort study of community-dwelling older adults. SETTING: Southern Tasmania, Australia. PARTICIPANTS: Seven hundred forty noninstitutionalized older adults (50% female; mean age 62��7) randomly sampled from electoral rolls. MEASUREMENTS: Dietary nutrient intake was examined at baseline and follow-up (2.6��0.4 years later) using The Cancer Council Victoria's Food Frequency Questionnaire (FFQ). Appendicular lean mass (aLM) was assessed using dual X-ray absorptiometry and muscle strength of the knee extensors using a dynamometer. RESULTS: Failing to meet the recommended dietary intake for protein was associated with significantly lower aLM at baseline (?0.81?kg, 95% confidence interval (CI)=?1.54 to ?0.08) and follow-up (?0.79?kg, 95%CI=?1.42 to ?0.17). http://www.selleckchem.com/products/byl719.html Energy-adjusted protein intake was a positive predictor of change in aLM over 2.6 years (��=0.10, P=.003). Energy-adjusted intake of iron (��=0.07, P=.02), magnesium (��=0.07, P=.02), phosphorus (��=0.07, P=.047), and zinc (��=0.08, P=.02) were positive predictors http://www.selleck.cn/products/gsk-j4-hcl.html of change in aLM, whereas retinol (��=?0.09, P=.005) was a negative predictor of change in aLM after adjustment for protein intake. No significant associations were observed between nutrient intake and muscle strength. CONCLUSION: Protein and several other dietary nutrients are associated with muscle mass and rate of muscle loss (but not strength) in older adults, suggesting that multiple dietary components may ameliorate the progression of sarcopenia. ""OBJECTIVES: To determine optimal hand-grip strength cut points for likelihood of mobility limitation in older people and to study whether these cut points differ according to body mass index (BMI). DESIGN: Cross-sectional analysis of data. SETTING: Data collected in the Finnish population-based Health 2000 Survey. PARTICIPANTS: One thousand eighty-four men and 1,562 women aged 55 and older with complete data on anthropometry, hand-grip strength and self-reported mobility. MEASUREMENTS: Mobility limitation was defined as difficulty walking 0.5?km or climbing stairs.