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When the entire sample is examined, these regressions explain between 66 and 72% of the size and shape variation for the glenoid, and between 63 and 75% of size and shape variation http://en.wikipedia.org/wiki/MERTK is explained for the condyle. Regression analyses for each species are highly variable; for all size variables, the lowest amount of variation is explained for P. paniscus, and these relationships are not significant when glenoid form is regressed on mandible length, TMJ-M1 distance, or skull centroid size. However, regression of mandibular condyle form identified statistically significant regression relationships for all taxa and all size variables. Visualization of the regression plot of LnMandLg demonstrates a stronger relationship between size and form than was observed when the specimens were fully GPA'd (Fig. 5). Again, glenoid form in Pan and Gorilla is strongly differentiated, and Pongo lies intermediate between these two groups. Furthermore, the distribution for P. paniscus is entirely separate from all other taxa. Only the angle between the regression trajectories for P. pygmaeus and P. abelii was statistically significant after Bonferroni correction (Table 8). In the mandibular condyle, regression of the scaled Procrustes residuals on LnMandLg results in a stronger overlap between Pongo and Gorilla, but the distributions for Gorilla and Pan remain similarly differentiated. No angles between the regression trajectories for the condyle were statistically significant after Bonferroni correction (Table http://www.selleckchem.com/products/Adrucil(Fluorouracil).html http://www.selleckchem.com/products/SRT1720.html 8). Incorporating the biomechanically relevant scaling variables into the V/CV matrix of the principal components analysis considerably changes the visualization of specimens in morphospace for both the glenoid and the condyle (Fig. 7). As with the regression analyses, I present only results for the V/CV using mandible length, but results for all analyses were very similar because of the high degree of covariance among the biomechanical scaling variables. When the glenoid fossa configuration is examined, PC 1 (which explains 67% of the shape variance) entirely separates the distributions for Pan and Gorilla, as well as P. paniscus and P. troglodytes. Again, Pongo is intermediate between Gorilla and Pan. G. beringei also loads more positively along PC 1 than does G. gorilla, although there is still considerable overlap between these two species. Unsurprisingly, this axis is strongly correlated with LnMandLg (r2=0.994, P