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For each eye, two consecutive measurements were taken, starting with the right eye. This technique has proved to give reliable and objective measurements of intraocular straylight (Coppens et?al. 2006; Van den Berg et?al. 2009). We analysed the straylight values of 1017 healthy phakic individuals from the GLARE study, who were without any ocular pathology such as glaucoma, diabetic retinopathy, macular degeneration, dry eye, amblyopia and cataract (LOCS III >1.5), to further confirm the repeatability of the test and to assess the difference in straylight between contra http://www.selleckchem.com/products/PD-0325901.html lateral eyes. We found no statistically significant or clinically relevant difference between straylight repeated measures. The differences between repeated log(s) values had a mean and standard deviation for the right eyes of 0.0042?��?0.0992 and 0.0034?��?0.1043 for the left eyes, corresponding to repeated measures standard deviations of 0.0702 and 0.0738, respectively. This yields an average standard deviation for repeated measures of 0.0720 (root mean square of 0.0702 and 0.0738), which remains stable with different levels of straylight (see Fig.?1A). The repeatability obtained is in agreement with the results reported by Coppens et?al. (2006), Cervi?o et?al. (2008), and others. The mean differences are virtually zero and statistically not significant, indicating that no learning effect exists. For the straylight differences between right and left eyes, we found a mean and standard deviation of ?0.0047?��?0.1158 log(s), respectively http://www.selleckchem.com/products/epz-6438.html (Fig.?1B). The standard deviation is higher as would be expected from the repeated measures http://www.selleck.cn/products/JNJ-26481585.html differences reported earlier (0.0720), as the differences between both eyes were based upon averages of two values for each individual eye. According to anova analysis, the statistical significance of this effect is p?