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3% (4 patients), infection in 1.3% (4 patients) and compression of the bladder (progressively increasing incontinence) in 0.3% (1 patient). There was no correlation between the incidence of complications and the surgical approach (P?=?0.393). Data about the complete progress of LC-volume over http://www.selleckchem.com/products/midostaurin-pkc412.html the whole follow-up period were complete in 48 cases. The median LC-volume was higher in patients with complications than in patients without (median volume 120?mL [range 20�C1800?mL]vs 83?mL [range 20�C500?mL], respectively; P?=?0.258). Patients with https://en.wikipedia.org/wiki/Ketanserin subclinical-LC occur with higher frequency.1,6 These resolve spontaneously and rarely become symptomatic requiring treatment. http://www.selleckchem.com/products/liproxstatin-1.html Diagnosis is mostly with US, although small LC can be obscured necessitating abdominal-CT in unclear/complicated cases. Meanwhile, clinically relevant LC might reach large sizes and/or cause many complications. The strict extraperitoneal access seems responsible for the absence of lymph drainage causing 2.4% symptomatic-LC (28/1163 patients). Interestingly, the reported total complication rate after EERPE is 9.68%, which renders the symptomatic-LC as the most frequent post-RP-complication.7 There is a wide range of differences in LC-incidence between studies, suggesting differences in the thoroughness of operation techniques, different identification methods or diagnostic imaging, but the actual etiological and preventive mechanism(s) of this phenomenon remain speculative. Several surgical devices have been investigated, hoping to achieve better hemostasis and reduce seroma formation. Some of our surgeons speculated an increase in LC-incidence after excessive electrocauterization of lymph vessels (LV), rather than ligation. This is consistent with the findings of Porter et?al.8 Furthermore, no significant effect of ultrasonic scalpel was reported,9 which suggests ligation of lymphatics as an important aspect of PLND-technique.