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The more myopic eye exhibited increased initial NITM, DT, and DA as compared to the less myopic eye (0.21?��?0.16?D vs 0.15?��?0.13?D, p?=?0.026; 108.4?��?64.3?secs vs 87.0?��?65.2 secs, p?=?0.04; and 17.6?��?18.7?D*secs vs 12.3?��?15.7?D*secs, p?=?0.064), respectively. The difference in DA and the difference in SE between the more versus less myopic eye were significantly correlated (r?=?0.31, p?=?0.044). Furthermore, 63% (27/43), 56% (24/43), and 70% (30/43) of the more myopic eyes exhibited increased initial NITM, longer DT, and larger DA, respectively, than found in the less myopic eye. In approximately two-thirds of http://en.wikipedia.org/wiki/MRIP the anisometropic individuals, the initial NITM and its decay area were significantly increased in the more myopic eye as compared to the less myopic eye. NITM may play an important role http://www.selleckchem.com/products/pf-06463922.html in the development of interocular differences in myopia, although a causal relationship is yet to be established. Furthermore, the findings have potentially important implications regarding accommodative control and interocular accommodative responsitivity in anisometropia, in particular for anisomyopia. ""To compare and evaluate the agreement between keratometry readings using three devices: the Pentacam HR, the Orbscan IIz, and the TMS-4 topographer. In this prospective comparative study, 115 eyes from 115 healthy refractive surgery candidates were sequentially examined using three devices. Fourier analysis was used to evaluate corneal astigmatism in these subjects. The outcome measures comprised steep and flat keratometry readings, corneal astigmatism, the mean keratometry reading, and the J0 and J45 components. Repeated-measures analysis of variance (RM-anova) and Bland�CAltman plots with 95% limits of agreement were used to evaluate the difference between measurements. The mean keratometry readings were 43.89?��?1.51, 43.52?��?1.48, and 43.79?��?1.50?D using the TMS-4 topographer, the Orbscan IIz, and the Pentacam HR, respectively (p? http://www.selleckchem.com/products/AZD1152-HQPA.html mean, steep, and flat keratometry data were in better agreement using the TMS-4 topographer and the Pentacam HR. In general, the Orbscan IIz device measured lower values than either the TMS-4 topographer or the Pentacam HR. However, the corneal astigmatism measurements and the J0 component showed the best agreement using the TMS-4 topographer and the Orbscan IIz. The TMS-4 topographer and the Pentacam HR produced similar readings and can be used interchangeably to measure simulated keratometry values in young, healthy eyes.