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3 �� 0.8, 4.1 �� 1.1, 5.6 �� http://www.selleck.cn/products/CAL-101.html 2.6, and 6.0 �� 1.5, respectively. The CRLB for Glu was 14.9 �� 5.6 [%] in RUN-MC, and 14.3 �� 6.3 [%] in NTNU. Also, the macromolecular profile had a good fit (CRLB http://www.selleckchem.com/products/bay-57-1293.html in ROI numbers 3, 4, and 5 (P http://www.selleckchem.com/products/gsk2126458.html analysis of these differences led us to assess for a possible partial volume effects in these ROIs: we analyzed the relative contributions of gray matter, white matter, and CSF to these voxels (Table 2), which indeed differed between the institutions for some voxels (eg, ROIs 3, 4, and 5). To validate the reproducibility of the MRSI plane positioning we analyzed the offset of the MRSI plane between the repeated measurements. This differed 1.9 �� 1.3 mm in the RUN-MC cases and 1.4 �� 1.1 mm in the NTNU cases. The difference in angle between the line from nosetip to basis cranii and the transverse plane of the MRSI between the first and second measurement was smaller than 5�� in all cases (RUN-MC 1.6 �� 1.0��, NTNU 2.7 �� 1.4��). Taking the size of the VOI into account, this resulted in a deviation of the VOI tip-to-tip slice position (in feet�Chead direction) of 1.4 �� 0.8 mm for RUN-MC and 1.4 mm �� 0.7 mm for NTNU. The position of the MRSI slice in the repeated measurements in NTNU was ��5 mm higher above the ventricles than the position of the MRSI slice in RUN-MC.