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In each table, the RR of graft failure for African Americans, Hispanic/Latinos and Asians are compared with the RR for whites (RR http://www.selleck.cn/products/SP600125.html = 1.00). Without adjustments, the RR of graft failure at 5 years when compared with whites was 1.35 for African Americans, 0.83 for Hispanic/Latinos and 0.75 for Asians. All comparisons in Tables 5�C7 between the RR of graft failure for whites and other race/ethnicities are statistically significant with a p-value http://www.selleckchem.com/products/smoothened-agonist-sag-hcl.html survival for African Americans and Asians, and organ factors influenced outcomes for Asians. Adjustment for age alone resulted in an apparent increase in the RR of graft failure for minorities in comparison with whites (Table 5). Because white recipients were older, on average, than recipients from other racial/ethnic groups (Table 4), adjustment for age likely increased the expected number of graft failures for whites relative to minorities and, therefore, resulted in higher RRs for African Americans, Hispanic/Latinos and Asians. In contrast, whites had less pretransplant exposure to dialysis than did minority recipients. Because longer time on dialysis is associated with poorer graft survival, adjustment for time on dialysis increased the number of expected graft failures for African Americans, Asians and Hispanic/Latinos and decreased the RR of graft failure for these http://www.selleckchem.com/products/epz015666.html minority groups relative to whites. Therefore, adjusting for age tends to increase and, for duration of dialysis exposure, to decrease the RR of graft failure for each minority in comparison with whites. It is also notable that adjustment for the center factors included in these models closely parallels the results of an adjustment for center alone. In contrast, adjustment for age alone does not mimic the effect of adjustment for additional demographic factors among African Americans and Hispanic/Latinos. Therefore, center-alone is not maintained as a separate category in the stepwise analyses displayed in Tables 6 and 7, whereas age in these analyses continues to be analyzed separately from other demographic factors. The RR of graft failure by race/ethnicity at 5 years is shown for 11 models (1 unadjusted model and 10 models adjusted for an increasing number of factors) in Tables 6 and 7.