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2�C24.7 pulses s?1) and 1.4 �� 1.9 pulses s?1 (range 0.2�C6.8 pulses s?1) in the second interval (P? http://en.wikipedia.org/wiki/Diglyceride after 8.2 s from the end of the second activation and lasted 10 s. The average discharge rate during the third activation interval was very low (1 pulse s?1). Finally, 7 of 37 motor units discharged two to three fasciculation potentials after 12.0 �� 9.5 s from the end of either the first or the second activation interval. The average discharge rate of the fasciculations was 1.6 �� 1.8 pulses s?1 (range 0.2�C4.9 pulses s?1). The discharge variability of the motor units identified during the intact condition was higher than usually observed in http://www.selleckchem.com/products/AZD0530.html voluntary contractions (Enoka?et al.?1989; Macefield?et al.?2000; Moritz?et al.?2005). The correlation between the?nth and the (n?+ 1)th ISI values was non-significant for 8 of the 37 motor units (R?= 0.15 �� 0.07,?P?> 0.05). In the remaining motor units, the correlation was positive and significant, although the correlation coefficient value was rather low (R?= 0.32 �� 0.12,?P? http://www.selleckchem.com/products/GDC-0941.html in the same subject as in Fig. 4. These action potentials presented a small variability in shape and amplitude (NMSE 3.9%), so that they were considered as potentials discharged by an individual motor unit which was active for ?2 s. During the activation interval, this motor unit discharged with a peak rate of ?60 pulses s?1 and a minimum rate of ?8 pulses s?1. Similar to this case, it was possible to identify trains of action potentials with stable waveform over time in all other subjects. In total, 38 motor units were identified in the blocked condition (4.7 �� 2.1 motor units per subject, range 3�C9 motor units per subject). The variability of the motor unit action potential waveforms was low, as evidenced by the low values of NMSE (5.4 �� 5.1%), and not greater than the variability observed during voluntary contractions (Fig. 5). All motor units identified in the blocked condition were characterized by a short interval of activity and large range of discharge rate over the activation interval, as in the example of Fig. 7. The average interval of activation of the motor units identified in the blocked condition was 1.1 �� 1.0 s (range 0.08�C5.23 s; shorter than in the intact condition:?P?