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In comparison to men in the subcohort, the case group had significantly (p? http://www.selleckchem.com/products/Adriamycin.html in the intertrochanter for both cases and subcohort. Intertrochanteric vBMD was not measured in the proximal 10% of the medial (MA and MP) quadrants because these regions did not contain any bone. Cortical vBMD in all quadrants increased http://www.selleckchem.com/PD-1-PD-L1.html from proximal to distal, 0.55?g/cm3 or 260% on average in the anterior (MA and LA) quadrants and 0.21?g/cm3 or 76% on average in the posterior (MP and LP) quadrants. Trabecular and integral vBMD were lowest in the central third of the intertrochanter. Cortical and integral vBMD was 7% to 19% lower in the case group compared to the subcohort (p? http://www.selleck.cn/products/MK-1775.html in the superior (SA and SP) quadrants of the FN and the MP quadrant of the intertrochanter (Fig. 5). In the trochanter, cortical thickness was always greater than 2?mm in the anterior (MA and LA) quadrants with changes around 1?mm along the length: decreases in MA and increases in LA quadrants. It increased in LP from 1.5?mm to 3 to 5?mm, whereas it remained at 1 to 1.5?mm in the MP quadrant. Men in the case group had significantly thinner cortex than the subcohort throughout the proximal femur and the percentage differences in mean thickness ranged from 14% to 30%. Mean cross-sectional area of the fracture cases was 12.9 (95% confidence interval [CI], 12.3�C13.5) cm2 at the FN, 18.2 (95% CI, 17.2�C19.3) cm2 at the IT, and 20.7 (95% CI, 19.7�C21.8) cm2 at the TR, which were not significantly greater than the subcohort's values of 12.4 (95% CI, 12.1�C12,6) cm2 at the FN (p?=?0.09), 17.2 (95% CI, 16.8�C17.6) cm2 at the IT (p?=?0.06), but significantly larger than 19.5 (95% CI, 19.1�C20.0) cm2 at the TR (p?=?0.