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Compared to our laboratory's normal values for the lower leg (9.6, range 3.2�C17.4 fibers/mm) the median distal IENFD of male patients was markedly reduced (3, range 0�C13 fibers/mm; p http://www.selleckchem.com/products/epacadostat-incb024360.html had lower distal (p http://www.selleckchem.com/products/i-bet-762.html correlation was found between GFR and distal IENFD (Spearman's ��: 0.723; p http://www.selleck.cn/products/lee011.html nerve conduction studies, and presence of a recordable SSR did not change during 4-year follow-up (see Table 1 for a synopsis of the clinical data at follow-up.) Overall, the comparison of mean QST values in FD patients with matched controls showed worsening of SF function over time (Fig. 1B). At 2-year follow-up, patients (18 men, 9 women; only 2 women without ERT) had elevated detection thresholds for cold (?2.66 �� 0.34; p