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4% of measurements. Underestimations were more common in younger patients with the iGFR:eGFR ratio correlating http://www.selleck.cn/products/wortmannin.html inversely with increasing age (r?=??0.42, P?0.58 mls/min/1.73?m2/yr). Of the 71% with excess loss, there was no decline in eGFR in 32% and where excess loss of iGFR was >10% of baseline function this figure was 28.6%. Conclusions:?iGFR measurement is beneficial in the follow up of cystectomy patients. There are significant differences between eGFR and iGFR values and eGFR fails to detect loss of function in a large number of patients. P101 The Impact of Music on Pain and Anxiety Experienced in Patients Undergoing Flexible Cystoscopy: A Prospective Randomized Controlled Trial L Dixon, AIL Coscione, M Winkler Imperial Healthcare NHS Trust, Urology Department, Charing Cross Hospital, London, United Kingdom Introduction and Objective:?To ascertain the effect of music on patients�� experienced anxiety and http://www.selleckchem.com/products/LY294002.html pain whilst undergoing routine office-based flexible cystoscopies. Methods:?Patients scheduled for flexible cystoscopy over a one-month period were randomized into two groups. Those in group 1 listened to music during cystoscopy and those in group 2 did not listen to music. The degree of experienced pain and anxiety was determined through patients completing 100?mm visual analogue scales before and after cystoscopy. Both female and male patients were included. Whether the patients had previous cystoscopies was also recorded to evaluate the possible ameliorating effect of prior experience. Results:?One hundred patients were enrolled, fifty in group 1 and fifty in group 2. Demographic characteristics were comparable between the two groups. Before flexible cystoscopy patients http://www.selleckchem.com/products/CHIR-99021.html in group 1 (music) had a significantly lower mean pain (1.6) and anxiety (17.5) versus mean pain (8.3) and anxiety (37.2) in group 2 (P?