Hantzsch Reaction as a Method for Spectrofluorimetric Analysis of Penicillin G

A sensitive, selective, and validated spectrofluorimetric method is being described for the determination of penicillin G. The method utilizes this drug (as a source of the amine moiety) to react with acetylacetone and formaldehyde through the Hantzsch reaction. The faint yellow product of dihydropyridine derivatives was measured at an emission wavelength of 481 nm (after excitation at 416 nm).

Biochemistry Modern Applications welcome submissions related to above fields. Authors may submit their valuable work at: biochemistry@ewpsjournals.com