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New chemotherapeutic agents, such as taxanes, along with improved RT techniques as well as the use of EBV-directed cytotoxic T lymphocytes, likely will provide further advances in the management of these patients43, 44; whereas more efforts will have to made to minimize acute and late effects with the incorporation of chemotherapy and http://www.selleck.cn/products/lapatinib.html RT protectants and imaging-guided and risk-adapted RT. Supported by Grants P30-CA23099 and CA21765 and by the American Lebanese Associated Charities. ""SELMAN L.E., WILLIAMS J. & SIMMS V. (2012) European Journal of Cancer Care21, 87�C97. A mixed-methods evaluation of complementary therapy services in palliative care: yoga and dance therapy To inform service provision and future research, we evaluated two complementary therapy services: yoga classes and dance therapy [The Lebed Method (TLM)]. Both were run as 6-week group courses. Patients completed the Measure Yourself Concerns and Wellbeing questionnaire pre- and post-course. Mean change over time was calculated for patient-nominated http://www.selleckchem.com/products/PTC124.html concern and well-being scores. Qualitative data regarding factors affecting health other than the therapy and benefits of the service were analysed using content analysis. Eighteen patients participated (mean age 63.8 years; 16 female; 14 cancer diagnoses); 10 were doing yoga, five TLM, and three both yoga and TLM; 14 completed more than one assessed course. Patients' most prevalent concerns were: mobility/fitness (n= 20), breathing problems (n= 20), arm, shoulder and neck problems (n= 18), difficulty relaxing (n= 8), back/postural problems (n= 8), fear/anxiety (n= 5). Factors affecting patients' health other than the therapy were prevalent and predominantly negative (e.g. treatment side effects). Patients reported psycho-spiritual, physical and social benefits. Concern scores improved significantly (P http://www.selleckchem.com/products/Avasimibe(CI-1011).html implications for future research. Yoga and TLM may be of benefit in this population. ""The identification of oncogenic genomic alterations is expected to facilitate the development of new molecularly targeted therapies for cancer. EML4 (echinoderm microtubule-associated protein-like 4)-ALK (anaplastic lymphoma kinase) was recently identified as a transforming fusion gene in non-small cell lung cancer (NSCLC). A small-molecule tyrosine kinase inhibitor of ALK, crizotinib, shows pronounced clinical activity in the treatment of patients with NSCLC positive for EML4-ALK, and it has rapidly entered into daily clinical practice. This review focuses on the biology and clinical features of, as well as diagnostic testing for, EML4-ALK-positive NSCLC.