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D Lockie,1 C Nickson2 and Aitken Z2 1Maroondah Breastscreen, 2University http://www.selleckchem.com/products/MG132.html of Melbourne, Melbourne, Victoria, Australia Aim: Five per?cent of screened women are recalled for assessment due to abnormalities on mammography. Many women undergo Ultrasound and biopsy to reach an outcome. This study evaluates whether Digital Breast Tomosynthesis (DBT) at assessment would reduce the number of ultrasounds and biopsies required to reach a diagnosis. Method: The study was conducted at Maroondah BreastScreen service where clients receive 2D mammography (compression and cone views) and where biopsy and ultrasound rates are 21% and 50% respectively. During the study, 557 participants also received DBT imaging. Radiologists assigned separate RANZCR scores to 2D and 3D images. 3D scores could potentially upgrade, but not downgrade, investigations prompted by 2D image scores. For our analysis, we use 2D and 3D RANZCR scores to estimate the expected number of investigations that would have occurred http://www.selleckchem.com/products/Rapamycin.html under 2D versus 3D imaging, and compare positive and negative predictive values (PPVs and NPVs) of 2D and 3D RANZCR scores against final outcomes. We also compare the radiation dose of 2D versus 3D imaging. Results: Ninety-three cancers were diagnosed in the study group (16.8%). For the 83.2% of women with a benign final diagnosis, we estimate that DBT (instead of 2D imaging) would reduce biopsies from 16.7% to 11.8% (30% reduction (95%CI 27% to 34%, p?=?0.03)), and ultrasounds from 58.0% to 50.1% (13% reduction (95%CI 12% to 14%, p?=?0.03)). The PPV of RANZCR scores 4/5 was 82% for 2D imaging and 83% for DBT (p?=?0.9). The NPV of RANZCR score 3 was 84% for 2D imaging and 92% for DBT (p?=?0.06). Radiation dose was on average 0.5 units higher for DBT than 2D imaging (mean 4.3 versus 3.8 units, p? http://www.selleck.cn/products/Bleomycin-sulfate.html reduce the need for biopsies (by 30%) and ultrasound (by 13%) in BreastScreen assessment. B Mackie and H Warren-Forward University of Newcastle, New South Wales, Australia Aim: Breast cancer is the second most common cause of cancer-related death in Australian women, therefore early breast cancer detection is essential. Female radiographers currently conduct breast screening in Australia; however there is a projected shortage of breast screening radiographers. With many women already feeling apprehensive about attending a breast examination, possible proposals to fill this shortage must be carefully considered. Training male radiographers is one proposal however, this raises some gender concerns. This study aimed to investigate whether it would change women's willingness to attend breast screening if it were to be conducted by a male radiographer. Method: Participants had the choice of completing a paper-based or web-based survey.