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Mean intracellular pyruvate stores in control iPSCs at 3, 6 and 12?h were 3.4, 2.9 and 3.3?nmol/mg protein, respectively (Fig.?4A-iii). In contrast, those in the GSDIb-iPSCs were 8.6, 20 (P? http://www.selleck.cn/products/SP600125.html were 0.84, 1.3 and 1.5?��g/mg protein, respectively (Fig.?4A-iv). In contrast, those in the GSDIb-iPSCs were 1.6, 2.8 and 2.9 (P? http://www.selleckchem.com/products/smoothened-agonist-sag-hcl.html in the control hepatocytes, 1.0, 1.6 and 2.1?��g/mg protein; and in the PtH, 1.6, 2.6 and 3.9 (P? http://www.selleckchem.com/products/epz015666.html control iPSCs (Fig.?4C), and the mean intracellular lactate stores in control iPSCs at 0, 5, 10 and 30?min were 4.5, 6.2, 5.8 and 5.5?��g/mg protein, respectively. In contrast, those of the GSDIb-iPSCs were 8.4, 16.1 (P?