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4 �� 12.4 years vs. 52.6 �� 12.7 years, p = 0.3) during diagnosis of cancer. The characteristics of different common cancer groups (defined as occurrence in five or more cases in our cohort) were also shown in Table 2. Cervical cancer, ovarian cancer and NHL developed in young transplant recipients who were also relatively young at time of transplantation. On the other hand, the carcinoma of prostate, NMSC and colorectal cancer occurred more often in the elderly transplant recipients (mean age at diagnosis of PTM more than 60 years). This could be attributed to an older age at transplantation and the relatively long duration from transplantation to development of cancers in these patients. The mean time interval between kidney transplant and PTM was 7.1 http://www.selleckchem.com/products/blz945.html �� 5.4 years. Thirty-eight (12.7%) patients had PTM diagnosed within 1 year http://www.selleckchem.com/products/hydroxychloroquine-sulfate.html of transplant, 88 (29.4%) between 1 and 5 years, 95 (31.8%) between 5 and 10 years, 50 (16.7%) between 10 and 15 years, 20 (6.7%) between 15 and 20 years, 7 (2.3%) between 20 and 25 years and 1 (0.4%) over 25 years. Kaposi sarcoma, NHL and urologic cancers occurred in the early posttransplant period (within 5 years of transplantation) while the colorectal cancer and the cancer of oral cavity occurred late (more than 10 years after transplantation). Male patients tended to develop PTM earlier than female patients after kidney transplant (6.8 �� 5.3 years vs. 7.4 �� 5.4 years, p = 0.3). Compared with the general population, our kidney transplant recipients had approximately three times higher risk of development of any types of malignancy (Table 3). The risk was higher in female than male patients (3.58 vs. 2.58). If NMSC were excluded as in some other studies, the SIR would be 2.81 (95% CI 2.5�C3.16). The risks of NHL and kidney cancer were more than 10 times higher while the risks of colorectal cancer, lung cancer and liver cancer were http://www.selleck.cn/products/BafilomycinA1.html only slightly increased when compared with the general population. The exact risk of Kaposi sarcoma could not be calculated because of negligible number of cases in the general population. The risk of bladder cancer was much higher in females than in males while the risk of kidney cancer was higher in male transplant recipients. None of the cancers specified occurred less frequently in kidney transplant recipients than in the general population. SIRs of all cancers were further analyzed according to age at transplant, duration of follow-up and year of transplantation (Table 4). The risk was highest in patients