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Clin Transplant 2011: 25: E22�CE31. ? 2010 John Wiley & Sons A/S. Abstract:? Background:? Malaysia��s organ and tissue donation rates are among the lowest in the world. The study aims to explore the knowledge, attitudes, practices and behaviors regarding deceased organ donation and transplantation in the diverse ethnic communities in the state of Selangor, Malaysia. Methods:? A cross-sectional, population-based, computer-assisted telephone interview exploring multi-ethnic participants�� knowledge, attitudes, practices and behavioral on deceased organ donation and transplantation was conducted from February to April 2009. Results:? Although only 5.5% of the total participants (N?=?1174) reported that they have registered http://www.selleckchem.com/products/r428.html to be organ donor, a further 35.2% of those who have not register for organ donation indicated willingness to donate their own. Significant socio-demographic disparities with respect to knowledge and attitudes scores were observed. In particular, Malays (20.7%) indicated lower willingness to donate organs compared to the Chinese (36.6%) and Indians (51.4%) (p? 95% CI?=?1.05�C1.31), secondary school education (OR?=?1.46, 95% CI?=?1.05�C2.02), and Malay ethnicity (OR?=?0.18, 95% CI?=?0.03�C0.94). Conclusion:? Findings assist organ donation and transplantation organizations to reach out the diverse socio-demographic and ethnic communities with cultural-specific information about organ donation. ""Strategies to delay or avoid the long-term decline in renal function and progression to chronic kidney disease (CKD) in liver transplant recipients remain unclear. Our aim was to examine the change in estimated GFR (eGFR) from six?months after liver transplantation, and to identify modifiable factors associated with a faster rate of decline. This was a single-center retrospective study of 97 patients who underwent elective liver transplantation and survived ��5?yr. eGFR was estimated using the MDRD6-variable equation, and the annualized change in eGFR was determined using simple linear regression. The baseline eGFR was 75?mL/min/1.73?m2. Thereafter, eGFR declined at a mean rate of 1.08?mL/min/1.73?m2 per year. 49% had a decline in renal function greater than the rate expected with aging. Decline in eGFR was an independent predictor of CKD by five?yr post-transplant (p?=?0.001). Multivariate modeling found a higher baseline eGFR (p?
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