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The mean TRBF for session 2 for the http://www.selleck.cn/products/Cisplatin.html trained and novice grader was 45.29?��?9.28?��l/min and 44.39?��?7.36?��l/min, respectively. The coefficient of repeatability (COR) of session 2 TRBF values between the trained and novice grader was 8.09?��l/min. There is a grader learning effect which impacts the venous area measurements. Reproducible and repeatable retinal blood flow measurements were achieved among trained graders using doctorc software. ""Purpose:? To investigate morphological variations in the macular area with optical coherence tomography (OCT) after vitrectomy for diabetic fibrovascular proliferation. Methods:? We reviewed 108 cases using OCT 7�C15?months after vitrectomy. Of these, 32 received OCT within 3?months postoperatively. Morphological variations were categorized and correlated with visual outcome. Results:? Only 24 cases (21.4%) had no obvious abnormalities. The most frequent findings were epiretinal membrane (52.8%), macular thickening (37.0%) and macular http://www.selleckchem.com/products/3-methyladenine.html cysts (28.7%). Multivariate regression showed that diffuse macular thickening, loss of foveal depression and diffuse retinal thinning were significantly associated with poor visual acuity. Sequential OCT ( http://www.selleckchem.com/products/PD-0325901.html angiography and, more recently, optical coherence tomography (OCT) can be used to detect and document these alterations (Arend et?al. 1995; Stalmans et?al. 1999; Otani & Kishi 2000). Although fluorescein angiography is valuable in the assessment of various macular lesions and retinal vascular abnormalities, its usefulness in discerning macular changes after diabetic vitrectomy may be compromised by the mild diffuse hyperfluorescence in the posterior pole seen frequently in middle- and late-phase angiography. Furthermore, quantification of changes may not be possible.