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Moreover, donors after full-right lobe donation (Group 2) presented a statistically significant increase in serum total bilirubin at POD 1, 2 and 5 and a statistically significant prolongation in aPTT at POD 1, 2, 5 and 8 in comparison to Group 1. Living donor liver transplantation is an established treatment modality of end-stage liver disease that alleviates the shortage of cadaveric donor organs, offering at the same time the great advantage of scheduling the transplantation before the occurrence of serious decompensation of the recipient [24,25]. Although the safety of the donor is of crucial importance for the application of LDLT, there is considerable controversy regarding the real risks of donor hepatectomy. Moreover, http://www.selleck.cn/products/bmn-673.html the absence of a worldwide registry for living liver donation makes the accurate estimation of donor mortality and morbidity almost impossible. This single-center study presented an overall http://www.selleckchem.com/products/PD-0332991.html morbidity rate of 21% for the entire cohort of the 87 consecutive donor hepatectomies performed in our department between January 2002 and December 2009. No donor mortality was observed and no donor suffered a life-threatening complication. There was no statistically significant difference observed in donor mortality and morbidity between right lobe and left lobe or left lateral lobe donation, but right lobe donors underwent an operating procedure of longer duration, had a significantly longer hospital stay and required more autologous blood transfusions via cell saver when compared with left- or left lateral http://www.selleckchem.com/products/Everolimus(RAD001).html lobe donors. As mentioned above, no donor mortality was recorded in our study. In our opinion, the absence of donor deaths is mainly attributable to the complete and thorough evaluation of all potential donors. Important is also the fact that all donors and especially the ones after full-right or full-left lobe hepatectomy had a remnant liver volume equal to or more than 30%, as the use of donors with remnant liver volume