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After application of the exclusion criteria, 10,022 patients were included in the final analysis group. Patient characteristics are displayed in Table 1. Median survival time for the entire patient group was 12.61 months. A total of 8139 patients were confirmed to have died, and 1883 were censored at the time of analysis. The size of the analysis group diminished with increasing time from diagnosis, both due to patient loss and due to data maturity requirements for some analyses (ie, only patients diagnosed early in the 1998 to 2008 period had the potential to be 10-year survivors at time of analysis). Of the original group of 10,022 patients, 4684 were alive at 1 year, 1474 were alive at 2 years, 198 were alive at 5 years, and 8 were alive at 10 years. Conditional survival from diagnosis, 6 months, and 1, 2, 3, 4, and 5 years after diagnosis is displayed in Table 2. The percentage http://www.selleckchem.com/products/hydroxychloroquine-sulfate.html of patients http://www.selleck.cn/products/BafilomycinA1.html surviving for an additional 6 months or 1 year initially declined before ultimately increasing in long-term survivors. Figure 1 displays the conditional probability of surviving an additional 12 months at various time points by diagnosis period. A higher proportion of patients diagnosed from 2005 to 2008 survived 12 months from diagnosis and from 6, 12, and 18 months after diagnosis, with no significant difference seen in survival from 24 or 30 months. Table 3 displays the percentage of patients surviving an additional 2 years by age group and time since diagnosis. In the initial univariate Cox PH model, greater age was highly associated with mortality. Relative to the 18- to 39-year-old subgroup, hazard ratio (HR) of death was 1.86 (95% CI, 1.69-2.05) in the 40- to 59-year-old subgroup, 3.25 (95% CI, 2.95-3.59) in the 60- to 79-year-old subgroup, and 6.44 (95% CI, 5.60-7.39) in the ��80-year-old subgroup. In models including http://www.selleckchem.com/products/blz945.html age group, demographic factors significantly associated with survival from diagnosis included sex (HR of death, 1.09; 95% CI, 1.04-1.14; P