always in pain

I am always either in physical or mental pain, but often both at the same time. I am bipolar and am constantly depressed. I have been so angry at everything. Everything upsets me. People that are too happy even bug me. My biggest thing right now is when people get too close to me. I have a major personal bubble now. Sometimes I feel as if i'll lose it. The worse thing is when someone tells me to calm down or just be confident. I can't stand it and the anger just flares.