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Overnight fasting venous blood samples were collected in the morning. Laboratory test data included serum creatinine, fasting glucose levels, fasting lipid profiles and fresh urine samples. The study protocol was approved by the Institutional Review Board. The exclusion criteria were as follows: primary or secondary hyperparathyroidism, hyperthyroidism, chronic renal failure, liver cirrhosis and abnormal urinary tract on radiological http://www.selleckchem.com/products/midostaurin-pkc412.html imaging. Patients were determined to have MetS according to the latest definition of the IDF, using ethnicity- and sex-specific cut-off values for central obesity.[11, 13] Using IDF criteria, the MetS in South Korean adults was defined by central obesity (WC ��90?cm for men and ��85?cm for women) plus two of the following four factors: serum TG ��150?mg/dL, HDL-C concentration https://en.wikipedia.org/wiki/Ketanserin Pearson ��2-test and Cochran�CMantel�CHaenszel test. Multiple logistic regression analysis was used to determine the OR for having UA calculi according to MetS and its components. A P-value of less than 0.05 was considered statistically significant. The patients' mean age was 55.9 years (range 19�C93 years). Table?1 compares the characteristics of patients with and without MetS. http://www.selleckchem.com/products/liproxstatin-1.html Of the 712 patients, 347 (48.7%, 205 males, 142 females) had a diagnosis of MetS according to the IDF MetS definition.[13] Overall, the mean age of patients with MetS was significantly higher than that of patients without MetS (57.4?��?13.3 vs 54.5?��?14.9 years; P?=?0.006). The male-to-female ratio (1.44:1.64) did not differ between the two groups. There was no significant difference in the number of stone episodes between the two groups. The patients previously diagnosed with type 2 diabetes were twofold more prevalent than patients without MetS. There were marked differences with respect to age, BMI, WC, BP, TG, HDL-C and FBG between the two groups. Serum UA was significantly higher in the patients with MetS than those without MetS (5.7?��?1.6 vs 5.0?��?1.5 years; P?