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All patients received anti-Pneumocystis jiroveci prophylaxis during the first 6?months post-transplantation using sulfamethoxazole-trimethoprim at 80/400?mg every other day. Donor-related data collected were age, gender, weight, terminal serum creatinine, estimated creatinine clearance (CC; using the Cockcroft/Gault formula), CMV serostatus, and cold ischemia time. We also collected the following recipient pretransplant data: http://www.selleck.cn/products/bmn-673.html age, gender, original native kidney disease, time on dialysis, the administration or nonadministration of ESA, body mass index, the use of hypotensive medications (i.e. betablockers, diuretics, ACEIs, ARBs and vasodilating or central nervous system hypotensive agents), and CMV serostatus. We also considered the recipients�� immediate post-transplant data collected on days 5, 7, 14 and 30 for factors such as Hb, mean corpuscular volume (MCV), reticulocyte count, serum creatinine and CC (according to the Cockcroft/Gault formula), the type of immunosuppressants (frequency and dosage in mg/kg/day), the use of ESAs and, if relevant, ESA weekly dosage. Delayed graft function (DGF) http://www.selleckchem.com/products/Everolimus(RAD001).html was defined as the need for at least one dialysis session after day 1 post-transplant. Serum ferritin as well as parathormone levels were recorded at pretransplant and at day 30 post-transplant. CMV viremia tests were performed on a weekly basis during the first month post-transplant. Variables are expressed either as the mean?��?SD, or as a median (ranges), according to their distribution. For the univariate analysis, qualitative variables were compared by the chi-squared test or by Fisher��s exact test, as appropriate. Quantitative variables were compared by Student��s t-test or the Wilcoxon test, as appropriate. A P-value below 0.05 was considered statistically significant. We determined the parameters that were associated with anemia and allograft function, as assessed by serum creatinine at 1?month post-transplant. http://www.selleckchem.com/products/PD-0332991.html We used Student��s t-test with two-tailed, independent samples to assess univariate analyses between the two groups, with the significance taken as P?=?0.05. Risk factors for anemia and allograft function at 1?month post-transplant were defined using a multivariate, stepwise, logistical regression analysis that used initial inclusion criteria that had a significance of P?
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