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Furthermore, patients listed for LT with age >50?years had twice the risk of death on the WL (data not shown, OR?=?1.985, 95% CI?=?1.441�C2.735, http://www.selleckchem.com/products/ly2157299.html P??300?��g/l were not associated with long-term post-transplant survival in contrary to Weismuller et?al. [10]. However, we note that in the latter study, the authors did not report on results of SF either as continuous variable or as a categorical variable in their Cox proportional hazard model analysis to determine factors associated with post-LT outcome. The authors purely reported on a sub-group of patients (n?=?33) with SF?��?365?��g/l and transferrin saturation http://www.selleck.cn/products/s-gsk1349572.html according to their laboratory reference range (Germany) [10]. The above cut-off points are different to our local laboratory reference values of 20�C300?��g/l (UK). It is obvious from this description that reference values for SF are significantly different between countries and continents. Furthermore, it is not unusual to find different SF reference range between laboratories in the same country. This makes comparison between these studies, generalization and applicability of the published reports of SF as predictor of outcome in patients with ESLD limited. Therefore, it is unlikely that SF will have a role in the assessment of patients for LT or in the modification of current prognostic models http://www.selleckchem.com/products/z-vad-fmk.html such as MELD or UKELD to improve their prognostic capacity. We found recipient age, HCC and CIT?��?10?h were independently associated with post-LT survival, consistent with previous reports [9, 10, 36, 37]. Pre-LT MELD score and UKELD score were not associated with post-LT survival which was also consistent with published literature [5, 7]. DRI, or individual components of DRI other than CIT were not associated with post-LT survival which is contrary to the published reports [13, 38]. This is may be explained by the fact that the median DRI of our cohort (1.7) was significantly higher than median DRI reported for Feng et?al. and Schaubel et?al. data with median DRI reported by MELD group with a range of 1.2�C1.5.