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Under the same conditions, i.p. administration of gabapentin (500??mol/kg?1), a clinical-use analgesic for neuropathic pain, was used as a positive control and produced a statistically significant reversal (53%, P? http://www.selleckchem.com/products/BIBW2992.html A-836339 at the same dose also significantly produced reversal of SNL-induced decrease in PWT (33%, P? http://www.selleckchem.com/products/BKM-120.html nerve produced a decrease in PWT to mechanical stimulation with von Frey monofilaments 2 weeks following surgery (PWT?=?2.2?��?0.2��g, Figure?5A), demonstrating the development of mechanical allodynia. Administration of A-836339 attenuated CCI-induced mechanical allodynia in a dose-related manner (n?=?12) and produced a 71% effect http://en.wikipedia.org/wiki/SWAP70 (P?