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Quality scoring of these studies according to the Critical Review Form �C Quantitative Studies scale was undertaken by the same investigators, with full final agreement (Tables?I and SIV, supporting material published online). The median score was 10.5. Characteristics of the studies included in the meta-analysis are shown http://en.wikipedia.org/wiki/YES1 in Table?II. The eight studies included 84 children with CP in the intervention groups, 76 of whom felt positive effects. The comparison groups comprised 89 children, including 39 with CP. Twenty-one of the children with CP felt positive effects from continuation of their weekly physiotherapy and/or occupational therapy, or from sitting on a barrel or in an artificial saddle. The remaining 50 children were non-disabled, and no effect on postural control and balance was found in this http://www.selleckchem.com/products/carfilzomib-pr-171.html subgroup. The meta-analysis was performed on the overall sample of the selected clinical studies. All the studies showed a positive effect after treatment with hippotherapy or THR, although a statistically significant association was found in only three studies (data not shown; Bertoti,17 Kuczynski and S?onka,36 Shurtleff et?al.14). The DerSimonian�CLaird estimate of pooled OR was 25.41, 95% CI 4.35, 148.53, z=3.59, p http://www.selleckchem.com/products/azd9291.html a possible minor publication bias in favour of the null association. However, Begg��s adjusted rank correlation test indicated no evidence of a substantial publication bias (z=1.48, p=0.138). Knowledge of equine-assisted therapies, especially hippotherapy and THR, and their efficacy is continually increasing and is becoming more reliable and precise. We have performed the first known meta-analysis of the literature on hippotherapy or THR on patients with CP. Using pooled data from eight studies, we have found a statistically significant effectiveness of hippotherapy or THR among children with CP. Postural control and balance are important elements of motor tasks. Postural stability is essential for the accomplishment of increasingly complex motor skills and coordination. Several sensory deficits associated with CP, including problems with vision, proprioception, and cutaneous perception, may contribute to impaired postural and balance control.