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When an HPV type (either prevalent, or newly detected) was considered cleared, but again detected during follow-up it was defined as a re-infection or reactivation of that certain HPV type. The re-infection/reactivation rates per 1,000 person months of any-type hr-HPV and lr-HPV were lower when clearance was defined as having two consecutive HPV negative samples compared to when clearance was defined as having an infection followed by one negative sample, 30.8 [95% confidence http://www.selleck.cn/products/VX-809.html interval (CI): 19.1�C49.5] and 39.5 [95% CI: 27.1�C57.7] per 1,000-person months, compared to 60.0 [95% CI: 49.0�C73.4] and 51.7 [95% CI: 41.6�C64.2] per 1,000-person months. The definition of clearance, a positive test followed by two consecutive negative tests, gives therefore more certainty of clearance. This supports the use of the definition http://www.selleckchem.com/products/17-AAG(Geldanamycin).html of clearance, a positive test followed by two consecutive negative, in an epidemiological study like ours. To identify any potential factors influencing incidence and clearance, the following factors were analyzed; age (baseline), smoking (baseline), oral contraceptive pill (OCP) use, age at first sexual intercourse, sexual age (number of sexually active years) (baseline), type of sexual relationship, having a new sexual partner, lifetime number of sexual partners, gender of sexual partner(s), number of sexual partners in the past 3 months, number of sexual contacts in the past 3 months, ever diagnosed with an STI, condom use, and having multiple HPV infections. The categorical variables were individually analyzed in univariate analysis http://www.selleckchem.com/products/lgk-974.html using log-rank testing, for the continuous variables age and sexual age univariate cox-regression testing was used. Results from the univariate analysis were used to determine which variables should be included in the multivariate analysis: when its p-value was