Sjogren's Syndrome Support Group
Sjogren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases.
Has anyone gone to an allergist immunologist?
I went and he did blood work to test for many things.
One thing he discovered is that I have a genetic immune deficiency related to gamaglobulin.
He said I don't have enough defences for much of anything. My numbers are 1/2 that of the lowest acceptable count.
I went and he did blood work to test for many things.
One thing he discovered is that I have a genetic immune deficiency related to gamaglobulin.
He said I don't have enough defences for much of anything. My numbers are 1/2 that of the lowest acceptable count.
Did your doc say what specific deficiencies you have? Also, do you have any kind of treatment plan for his findings?
I did see a allergist/immunologist/rheumatologist recently, but I was there for second opinions, and he was uninterested in helping me.
They put a lot of peces of the jigsaw together for me. The thing that gets me is that none of the 10 Dr's or 6 specialists which I have seen over the last 4 years tested for heavy metal poisening, specifically Mercury poisening until I saw an Enviromental Specialist recently. This specialist did and what do you know I have mercury poisening. It looks like it could be causing the CFS/Fibro, the IBS-d and there are strong links to causing Auto Immune diseases like Alzimers and Sjogrens.
Animal the question for your Immunologist is what is the cause for the low gamaglobulin?
Is some other imbalance causing the low gamaglobulin?
I am very low in Cobalt which is why Vitamin B injections help so much as the Mercury mycoplasm are robbing the mitocondrea of this vital trace element hence the fatigue.
Al
A test that detects and measures the various immunoglobulins in the blood. In the normal assay no monoclonal antibodies are detected. In multiple myeloma and chronic lymphocytic leukaemia a single clone of lymphocytes can produce one type of immunoglobulin that is detected in the electrophoresis as monoclonal (made by one cell clone). Gamma globulin, also called immunoglobulin is a class of blood plasma proteins, most notably including the antibodies that help fight infections and disease. Abnormal amounts of gamma globulin can have adverse effects on health or can be indicative of disease. In medicine, gamma globulin injections are used to treat certain conditions.
Gamma globulin injections can help boost a patient's immune system temporarily, so they are sometimes administered after a patient has been exposed to a contagious illness, though this practice is less common than it once was. This type of gamma globulin injection was formerly common for measles and hepatitis A, but vaccines currently exist for both conditions. Gamma globulin injections may also be given to patients who do not produce enough antibodies on their own as the result of a genetic disorder or an acquired condition.
Gamma globulin may also be used to treat immunological diseases other than deficiencies. For example, in immunological thrombocytopenia purpura, the patient's antibodies attack his or her own platelets, interfering with the blood's ability to clot. Gamma globulin injections are useful in treating this condition, though the mechanism by which they work is not fully understood. The injections may cause the spleen to ignore signals to destroy the antibody-tagged platelets, or they may cause the malfunctioning gamma globulin to degrade at an increased rate. In any case, the extra gamma globulin counteracts the malfunctioning antibodies that attack platelets and allows the platelets to thrive.
Since antibodies are used to fight infection, an unusually high amount of gamma globulin in the body, a condition known as hypergammaglobulinemia, is often a sign of infection. A proliferation of abnormal gamma globulin, or paraproteins, is likewise a sign of immune malfunction. Diseases of the gamma globulin such as this are called gammopathy. Gammopathy in itself may not be harmful, but it may be the sign of a serious immune condition, such as AIDS, or progress to a dangerous condition, such as nerve damage or plasma cell cancer. Therefore, close monitoring is advised.
My doc is doing more testing and is very interested in treating this defency.
He said the treatment is life long.
He said something about an ultra pure form and at some point will be subcutainious monthly once it is under control.