Sjogren's Syndrome Support Group
Sjogren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases.
Plaquinil affects the autoimmune system - so it can help with dry eye and dry mouth, but it does not specifically act on that. Evoxac or salagen directly affect the moisture producing glands. By affecting the autoimmune system, plaquinil can help with pain, dry eyes, dry mouth, fatigue - etc because the autoimmune system being out of whack is what caused those issues. Does that make sense?