Polymyositis & Dermatomyositis Support Group
Polymyositis (PM) is a type of chronic inflammation of the muscles (inflammatory myopathy) related to dermatomyositis and inclusion body myositis. The inflammation is predominantly of the endomysium in polymyositis, whereas dermatomyositis is characterized by primarily perimysial inflammation.
http://arthritis.about.com/od/inflammation/f/cytokines.htm
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785020/
http://www.ncbi.nlm.nih.gov/pubmed/16769651
http://www.ncbi.nlm.nih.gov/pubmed/19726994
http://www.metaphysical.ca/IIM/causes.html
An inflammatory cytokine or autoimmune processes are induced by microbial bacteria. A pathogenic microbe might cause disease directly. A cytokine is a convoluted, complex INDIRECT method of infection. For example, a tuberculosis infection (pathogenic) induces an inflammatory cytokine that then itself causes severe tissue damage. Cytokines come out of infectious pathogens (bacteria).
Our chemoprophylaxis medications kill microbial bacteria, parasites and fungi.
Here is another analogy...a hurricane is like a pathogen and the outer squall line bands of rain are like cytokines spinning off the hurricane.
I have an article, but I think Nanny gave us plenty to read on the subject.
I hope this helps. Best Wishes.