I was taking Azathioprine 75mg/day for a year.
It help me. Now i am in remission.

Michael Pm

hey freelee!
i've taken imuran (azathioprine) for a long time now. in the past this drug has helped me go into remission with my dm. i've been on it with this most recent relapse of dm for a few months shy of a year.

in the beginning it can make a person REALLY nauseous, but generally your body will get used to it. how much are you taking per day? i take 150 mg and my doc initially started me out the first week taking 50mg which made me just feel kinda like i could be sick all the time. then of course i went up 50mg per week.

you MUST take this medicine with a meal. not a snack, but a meal. drink LOTS of water all throughout the day. the nausea should get better in time. if you're taking more than 50mg make sure you split the dosage. i take 50mg in the morning with breakfast and i take the other 100mg w/dinner.

usually i get a minimum of one side effect with each medicine i try because i'm just really sensitive which is why i don't take anything unless absolutely necessary, but with imuran i did pretty good. i did find myself having more issues with heart burn once he bumped me up even further to 150mg, but my doctor put me on a medicine for a few weeks for that and i feel MUCH better.

that's my story! hope you're doing ok with it and that it can start helping you to feel better!

A couple of weeks ago my rheum took me off the Imuran. For the last 2 weeks i was on it I'd been getting real sick to my stomach and if I didn't take Imuran on a full stomach I'd feel even worse. Turns out that Imuran had been irritating my liver. I had a liver biopsy before the dx of PM because we couldn't figure out what was wrong with my liver, so the nausea could be a flare in the disease or a reaction to the drug..?

I can't assist with advice on this one..I don't take Imuran I take Methotrexate :( Both suck lol

thanks for the replies - I like the word remission - it makes me smile.
i am on only 1 tab (ipresume 50 but too lazy to walk upstairs and check) for 6 weeks and them double so i will take your god advice and split dose. Thanks.

if you really have a hard time with the nausea just talk to your doctor about it to see if they can give you something to help you out with that. otherwise just remember lots of water and food with your medicine. your doctor might advise you to take one in the morning one in the evening too. i hope it helps & you can find remission like i have in the past. good luck & keep us updated! :)

Have taken Imuran twice in my life... always split the dose, have never been nauseous. One of the luck few i guess. Made my hair thinnger.

@freelee: REMISSION, REMISSION,REMISSION, REMISSION, REMISSION, REMISSION, REMISSION, REMISSION, REMISSION.

Hope you smile lots over the Holidays!
Merry Christmas.