I'm not certain the LDN is working. or maybe it's just this awful disease. I have been under some pretty heavy emotional pain and I am having the worst flare of RA I've had since I was first diagnosed last October. For the first time last night I had to wear a wrist brace to bed. My right wrist felt like I broke it, it was so painful to move. This morning I have swelling in most of my joints. I was exhausted last night (RA fatigue I think). Then I woke up feeling like this. It's discouraging. Maybe I need a two night break from the LDN this weekend. I think it would be a good idea.

What is the max dosage anyone is taking of LDN? I am on 4.5 and I'm wondering if a higher dose would be of any additional benefit.

Thanks