Dealing with Diabetes2 and remembering Goldi Community Group
A support group for individuals with Type2 diabetes. Encouragement, empathy, advice, and personal experiences from members dealing with the illness. A friendly environment with compassion and support as our main objective.
The big problem with these new drugs is that it take's about 10 years for the patent protection to run out and so are usually very expensive to prescribe.
I guess the only ++++ is that any side effects are usually found by that time
Statins: combined pill for diabetes and heart disease in pipeline
Scientists are developing a new class of drug which tackles both heart disease and Type 2 diabetes and has the potential to be more effective than statins.
Scientists are examining a new class of drug that work in a different manner, called cholesterol ester transfer proteins (CETPs) Photo: ALAMY
By Stephen Adams, Medical Correspondent9:00PM BST 18 Jul 20114 Comments
The drugs both raise the level of "good" (HDL) cholesterol and stabilises blood sugar levels, reducing the risk of heart disease and diabetes.
Scientists investigating the effects of this type of drug in trials of patients with adult-onset diabetes believe it could give them "real benefits".
Some 2.5 million people in Britain suffer from Type 2 diabetes, which can be brought on by eating too much and exercising too little, lifestyle factors that also raise the chances of heart disease.
Many are put on statins to lower the levels of "bad" (LDL) cholesterol in their blood, which is proven to reduce the number of heart attacks and other cardiovascular events.
However, now scientists are examining a new class of drug that work in a different manner, called cholesterol ester transfer proteins (CETPs).
Early trials of one such drug, called torcetrapib, showed that when given in conjunction with a statin to lower levels of bad cholesterol, levels of good cholesterol rose by 67 per cent. Those given the statin alone saw no such change.
HDL, or good cholesterol, is important because it has the protective effect of slowing the hardening of the arteries.
Patients on both drugs had blood sugar levels some seven per cent lower compared to those given just the statin. Insulin resistance, another measure of diabetes, also improved.
However, in 2006 this trial was stopped because it was found that giving both drugs resulted in more cardiovascular problems and deaths. Now, however, scientists have determine that these negative effects were the result of torcetrapib alone, and not the entire class of drugs.
Two other drugs from the same class, called dalcetrapib and anacetrapib, are being developed.
Prof Philip Barter, of the Heart Research Institute at Sydney University, said: "The possibility that CETP inhibitor drugs may not only reduce the risk of heart attack and stroke, but may also improve the control of blood sugar in people with diabetes, is an exciting prospect that may translate into real health benefits for people with diabetes."
A spokesman for the British Heart Foundation said it was too early to comment on whether dalcetrapib and anacetrapib would make suitable candidates for drugs.
I guess the only ++++ is that any side effects are usually found by that time
Statins: combined pill for diabetes and heart disease in pipeline
Scientists are developing a new class of drug which tackles both heart disease and Type 2 diabetes and has the potential to be more effective than statins.
Scientists are examining a new class of drug that work in a different manner, called cholesterol ester transfer proteins (CETPs) Photo: ALAMY
By Stephen Adams, Medical Correspondent9:00PM BST 18 Jul 20114 Comments
The drugs both raise the level of "good" (HDL) cholesterol and stabilises blood sugar levels, reducing the risk of heart disease and diabetes.
Scientists investigating the effects of this type of drug in trials of patients with adult-onset diabetes believe it could give them "real benefits".
Some 2.5 million people in Britain suffer from Type 2 diabetes, which can be brought on by eating too much and exercising too little, lifestyle factors that also raise the chances of heart disease.
Many are put on statins to lower the levels of "bad" (LDL) cholesterol in their blood, which is proven to reduce the number of heart attacks and other cardiovascular events.
However, now scientists are examining a new class of drug that work in a different manner, called cholesterol ester transfer proteins (CETPs).
Early trials of one such drug, called torcetrapib, showed that when given in conjunction with a statin to lower levels of bad cholesterol, levels of good cholesterol rose by 67 per cent. Those given the statin alone saw no such change.
HDL, or good cholesterol, is important because it has the protective effect of slowing the hardening of the arteries.
Patients on both drugs had blood sugar levels some seven per cent lower compared to those given just the statin. Insulin resistance, another measure of diabetes, also improved.
However, in 2006 this trial was stopped because it was found that giving both drugs resulted in more cardiovascular problems and deaths. Now, however, scientists have determine that these negative effects were the result of torcetrapib alone, and not the entire class of drugs.
Two other drugs from the same class, called dalcetrapib and anacetrapib, are being developed.
Prof Philip Barter, of the Heart Research Institute at Sydney University, said: "The possibility that CETP inhibitor drugs may not only reduce the risk of heart attack and stroke, but may also improve the control of blood sugar in people with diabetes, is an exciting prospect that may translate into real health benefits for people with diabetes."
A spokesman for the British Heart Foundation said it was too early to comment on whether dalcetrapib and anacetrapib would make suitable candidates for drugs.
One that won't make me sick
One that won' make me crash my car
Or make me feel three feet thick
I want a new drug
One that won't hurt my head
One that won't make my mouth too dry
Or make my eyes too red
On a serious note, I have a higher good cholestrol and lower bad cholestrol although that was awhile back and I had stop taking my Vitamins and my doctor was shocked how it was so good although I am back to taking it once again so I hope to have it all checked again before the end of the year although he is careful with the medicaid expenses so it could be in the year 2012, I am hoping for the best news. I think the LD is the worse and I am including Triglycerides, maybe someone knows better than moi. I found the older reports of my blood so maybe I will discuss this when I have it all in hand.