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Insulin injections for diabetics just once monthly with new 'jelly' substance being tested
Diabetics could be given monthly injections of insulin instead of several daily after scientists devised a slow release 'jelly', it has emerged.
Traditional insulin needs to be injected frequently to keep blood sugar levels stable but even then it creates 'peaks and troughs' as the body processes it quickly which can cause complications Photo: ALAMY
By Rebecca Smith, Medical Editor
7:30AM GMT 29 Jan 2013
Comment
Early stage tests suggest the new substance could dramatically cut the number of injections type 2 diabetics need, researchers at Duke University in America said.
Traditional insulin needs to be injected frequently to keep blood sugar levels stable but even then it creates 'peaks and troughs' as the body processes it quickly which can cause complications.
Scientists have been working to find a way to deliver the drug in an even way over time.
Engineers have created a liquid that turns to jelly once injected under the skin and leaches out its active ingredient gradually.
Tests on mice showed it kept blood sugar levels stable for five days, 120 times longer than normal.
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Ashutosh Chilkoti, professor of biomedical engineering in Duke's Pratt School of Engineering, and lead author of the study said: "For a patient with type 2 diabetes, it would be much more desirable to inject such a drug once a week or once a month rather than once or twice a day.
"Additionally, this approach avoids the peaks and valleys of drug concentrations that these patients often experience."
Other drugs could be delivered in the same way.
The findings were published in the journal Proceedings of the National Academy of Sciences.Insulin injections for diabetics just once monthly with new 'jelly' substance being tested
Diabetics could be given monthly injections of insulin instead of several daily after scientists devised a slow release 'jelly', it has emerged.
Traditional insulin needs to be injected frequently to keep blood sugar levels stable but even then it creates 'peaks and troughs' as the body processes it quickly which can cause complications Photo: ALAMY
By Rebecca Smith, Medical Editor
7:30AM GMT 29 Jan 2013
Comment
Early stage tests suggest the new substance could dramatically cut the number of injections type 2 diabetics need, researchers at Duke University in America said.
Traditional insulin needs to be injected frequently to keep blood sugar levels stable but even then it creates 'peaks and troughs' as the body processes it quickly which can cause complications.
Scientists have been working to find a way to deliver the drug in an even way over time.
Engineers have created a liquid that turns to jelly once injected under the skin and leaches out its active ingredient gradually.
Tests on mice showed it kept blood sugar levels stable for five days, 120 times longer than normal.
Related Articles
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Ashutosh Chilkoti, professor of biomedical engineering in Duke's Pratt School of Engineering, and lead author of the study said: "For a patient with type 2 diabetes, it would be much more desirable to inject such a drug once a week or once a month rather than once or twice a day.
"Additionally, this approach avoids the peaks and valleys of drug concentrations that these patients often experience."
Other drugs could be delivered in the same way.
The findings were published in the journal Proceedings of the National Academy of Sciences.
Diabetics could be given monthly injections of insulin instead of several daily after scientists devised a slow release 'jelly', it has emerged.
Traditional insulin needs to be injected frequently to keep blood sugar levels stable but even then it creates 'peaks and troughs' as the body processes it quickly which can cause complications Photo: ALAMY
By Rebecca Smith, Medical Editor
7:30AM GMT 29 Jan 2013
Comment
Early stage tests suggest the new substance could dramatically cut the number of injections type 2 diabetics need, researchers at Duke University in America said.
Traditional insulin needs to be injected frequently to keep blood sugar levels stable but even then it creates 'peaks and troughs' as the body processes it quickly which can cause complications.
Scientists have been working to find a way to deliver the drug in an even way over time.
Engineers have created a liquid that turns to jelly once injected under the skin and leaches out its active ingredient gradually.
Tests on mice showed it kept blood sugar levels stable for five days, 120 times longer than normal.
Related Articles
Ashutosh Chilkoti, professor of biomedical engineering in Duke's Pratt School of Engineering, and lead author of the study said: "For a patient with type 2 diabetes, it would be much more desirable to inject such a drug once a week or once a month rather than once or twice a day.
"Additionally, this approach avoids the peaks and valleys of drug concentrations that these patients often experience."
Other drugs could be delivered in the same way.
The findings were published in the journal Proceedings of the National Academy of Sciences.Insulin injections for diabetics just once monthly with new 'jelly' substance being tested
Diabetics could be given monthly injections of insulin instead of several daily after scientists devised a slow release 'jelly', it has emerged.
Traditional insulin needs to be injected frequently to keep blood sugar levels stable but even then it creates 'peaks and troughs' as the body processes it quickly which can cause complications Photo: ALAMY
By Rebecca Smith, Medical Editor
7:30AM GMT 29 Jan 2013
Comment
Early stage tests suggest the new substance could dramatically cut the number of injections type 2 diabetics need, researchers at Duke University in America said.
Traditional insulin needs to be injected frequently to keep blood sugar levels stable but even then it creates 'peaks and troughs' as the body processes it quickly which can cause complications.
Scientists have been working to find a way to deliver the drug in an even way over time.
Engineers have created a liquid that turns to jelly once injected under the skin and leaches out its active ingredient gradually.
Tests on mice showed it kept blood sugar levels stable for five days, 120 times longer than normal.
Related Articles
Fizzy drinks linked to prostate cancer risk 28 Nov 2012
NHS care hit by more rationing, claims report 18 Nov 2012
Hundreds of patients subjected to NHS blunders 29 Oct 2012
Ashutosh Chilkoti, professor of biomedical engineering in Duke's Pratt School of Engineering, and lead author of the study said: "For a patient with type 2 diabetes, it would be much more desirable to inject such a drug once a week or once a month rather than once or twice a day.
"Additionally, this approach avoids the peaks and valleys of drug concentrations that these patients often experience."
Other drugs could be delivered in the same way.
The findings were published in the journal Proceedings of the National Academy of Sciences.
meal planning to go with the insulin dose