Married 25 years! One son in college. We are currently dealing with a huge amount of stress. #1) My wife's father, who has been in a nursing home for 10 years, is now in a hospice, awaiting death. She flew up there today. #2) Me. I had sinus surgery back in June. Was doing OK, then got sick again. Long story, but having surgery again next week. Have been on IV antibiotics with a PICC line for 7 weeks, 3 more to go. I am on pain, sleep, and anti-anxiety meds right now. Pain/Sleep is because due to my sinus issue, I cannot lay down, and am in a lot of facial pain most of the day. This includes panic attacks, migraines, and an ER trip two weeks ago from a panic attack I could not control. So, she has been having to deal with me and be my caregiver for the last 4-5 months. However, the main reason I am freaking out is how my wife looks. She has not has regular checkups in 20 years. Over the last year, she has lost A LOT of muscle mass (very visible), and has a chronic, dry cough, and just looks terrible. I don't know how much weight she has lost, but it is significant. 2 years ago, she was quite overweight. I am thinking, Cancer. She hates her job also. He best friend was just diagnosed with Cancer. I asked her a few months ago to please get a checkup. She said she is under too much stress, and will "go when she is ready." She is really going to explode from the weight of all of this, and I think she knows something is wrong, but is in denial. The stress it is causing me of not knowing what is wrong with her is unbearable, and a big factor in my daily anxiety. When I look at her, I want to cry. How do I bring this up again with her, given all that is going on? THanks.