What Gut Bacteria Might Have To Do With Colorectal Cancer Risk

Researchers from the Icahn School of Medicine at Mount Sinai found that giving antibiotics to mice to disrupt their microbial gut population led to the prevention of polyp formation (polyps are early tumors that can eventually become cancerous). The findings suggest gut bacteria may have some sort of effect on the formation of tumors in the intestines. Healthy cells turn cancerous because of gene mutations, but researchers noted that there are some instances of colorectal cancer that seem to only occur at certain parts of the intestine. Because of this, the researchers suspected that there could also be a non-genetic factor at play. "In addition to genetic changes, various lifestyle-related factors, such as obesity and diet, have been linked to colorectal cancer . Some of these lifestyle factors appear to affect the types of bacteria present in the gut," study researcher Dr. Sergio Lira said in a statement. "Ultimately, understanding the interplay between genetic mutations, gut microbes and inflammation may lead to novel diagnostics and therapies for intestinal cancer." The findings are published in The Journal of Experimental Medicine . According to the Mayo Clinic, other known risk factors for colon cancer include older age, race, having an inflammatory intestinal condition, having a family history of colon cancer or polyps, consuming a diet high in fat and low in fiber, being obese, having diabetes, leading a sedentary lifestyle and consuming high amounts of alcohol. Get top stories and blogs posts emailed to you each day. Facebook web site http://www.huffingtonpost.com/2014/03/05/gut-bacteria-colorectal-cancer-intestinal-tumors_n_4890967.html












Do Colon Polyps Shrink With Fiber Intake?





Last Updated: Aug 16, 2013 | By Aubri John Photo Caption A meal of beans and rice is fiber rich and can help lower your risk of polyps when eaten regularly. Photo Credit Jupiterimages/Comstock/Getty Images A colon polyp is a clump of abnormal cells that forms on the lining of your large intestine, or colon. In most instances, you may not know you have colon polyps because they generally do not cause symptoms. Polyps may take years to form and over time become larger, increasing your risk of the polyp turning cancerous. A high-fiber diet can help reduce your risk of polyp formation and may shrink existing benign polyps. Risk and Treatment A variety of factors can increase your risk of polyp formation, including age, family history of polyps, dietary habits, use of alcohol or tobacco, being overweight and a sedentary lifestyle. Untreated colon polyps can grow, multiply or become cancerous, and it is imperative if you are age 50 or older to get annual screenings to detect and treat polyps early. Once a polyp is detected, your physician may remove it immediately to reduce the chance of it growing and turning cancerous. Removal of polyps is the first line of treatment, but you can help prevent recurrence by increasing your daily fiber intake. You Might Also Like Diet to Prevent Colon Fiber and Colon Polyp Research Preliminary research from the University of California, Davis, indicates that a diet high in fibrous vegetables and vitamin D-3 may shrink existing colon polyps to the point of disappearance. According to the Colorectal Cancer Association of Canada, the researchers from the UC Davis study hypothesize that a chemical called butyrate, a fatty acid, in the fibrous foods may be the component causing shrinkage. click this over here now http://www.livestrong.com/article/529045-do-colon-polyps-shrink-with-fiber-intake/