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For the five points with statistical significance, the significance is weak (P?=?0.018�C0.034) but the data indicates that the control (shaving) is actually superior to the active (hot-wire) treatment. These points all occur during the active treatment phase. In the follow-up phase, the p values are 0.252, 0.0972, and 0.230 at 1, 2, and 3 months, respectively, which indicates that shaving and hot-wire are not statistically different from one another in terms of regrowth at any point in time during the post-treatment phase of the study. Figure 8 plots the mean percentage change from baseline in hair http://www.selleckchem.com/products/BAY-73-4506.html counts for the active and control sites, that is cfb (%)?=?(count???baseline)/baseline?��?100, which normalizes the data. It can be seen from the figure that The control and active results overlay each other to a high degree at all time points. The degree of difference at any time point is small compared http://en.wikipedia.org/wiki/Anaplastic_lymphoma_kinase to the measurement range indicated by the boxes at that time point, shaving is generally slightly more effective than the hot-wire device in removing hair during the treatment period but the difference is small, both shaving and hot-wire essentially maintain the shaved baseline hair counts throughout the treatment period, although there is a slight increase in hair in the later phases of treatment, there is a substantial increase in hairs in the follow-up period after cessation of shaving and hot-wire treatments, there is no measurable difference between shaving and the hot-wire device in the follow-up period. The percentage change from the baseline is generally not statistically significant for either the control or active treatment during the treatment phase, but after treatment has stopped, the hair regrows promptly and the percentage change from baseline is strongly significant (generally, P? http://www.selleckchem.com/products/BIBF1120.html immediately after stopping treatment. To better compare the normalized active and control to each other, Figure 9 plots the difference in percentage change from baseline in hair counts between the active and control sites. This definitive figure shows that the mean normalized difference between the treatments is very close to zero at every time point, ranging from only ?4.9 to 4.9% points, and that any excursions from zero are small compared to the measurement range. The t-test P-values are high, ranging from P?=?0.154�C0.890 over all the time points in the study and P?=?0.360�C0.890 during the 1, 2, and 3 month follow-up period. Thus, we can safely conclude that there is no statistically significant difference in hair counts between the hot-wire device and shaving in this study, and, thus, that the hot-wire device did not suppress, inhibit, or reduce hair regrowth, change the rate of or otherwise delay hair regrowth, or effect permanent or long-term hair reduction.