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The transition between these components occurred approximately at the time of tooth�Cfood contact. During the masticatory sequence, when the food was particularised, the size of the early component as well as the peak amplitude of the EMG significantly decreased along with a reduction in the duration of the jaw-closing phase. Except for amplitude scaling, food hardness did not appreciably affect the muscle's activation profile. In conclusion, http://www.selleckchem.com/products/dabrafenib-gsk2118436.html when chewing food during natural conditions, masseter muscle activation adapted throughout the masticatory sequence, principally during the jaw-closing phase and influenced both early and late muscle activation components. Furthermore, the adaptation of jaw actions to food hardness was affected by amplitude scaling of the magnitude of the muscle activity throughout the masticatory sequence. ""This study aimed to analyse occlusal force, area and pressure for individual maxillary and mandibular teeth by assessing their occlusal-supporting abilities. Ninety-nine subjects (49 men and 50 women; average age, 24��7?��?3��4?years; range, 20�C37?years) performed maximal voluntary clenching twice for 3?s in both the intercuspal position and the intercuspal position with sliding movement from edge-to-edge occlusion, with a pressure-sensitive sheet placed between the maxillary and mandibular dental arch. Occlusal force, area and pressure of individual teeth were calculated by colour development in the pressure-sensitive sheet with special analytical equipment and software. Occlusal contact condition of individual teeth http://www.selleckchem.com/products/bmn-673.html was confirmed using the intra-occlusal record. All data were analysed using unpaired Student's t-test, Kruskal�CWallis test and Scheffe's test for multiple comparisons with a significance level of P? http://www.selleck.cn/products/abt-199.html occlusion was adopted as the representative occlusal-supporting ability for each individual tooth, although there were, in part, statistically significant differences in the effects of laterality, performance and gender. Overall, the occlusal pressure increased gradually from the central incisor, peaked at the canine or first premolar and decreased sharply�Cand significantly (P?