Potential New Drug For Inflammatory Bowel Disease

It blocks immune system cells that release proteins called cytokines that trigger inflammation, causing tissue damage and diarrhea to move into the small intestine and colon. The targeted nature of the medication helps reduce troublesome side effects such as weight gain, nausea and headaches caused by other treatment options. Current treatments such as steroids and immunosuppressive medications broadly suppress the immune system, which can also put the patient at risk for infections. Inflammatory bowel disease causes severe ongoing bouts of illness that adversely affect a patients quality of life at home and work, said Sandborn. These latest findings will potentially lead to a new drug therapy that will improve a patients overall lifestyle. Crohns disease and ulcerative colitis are forms of inflammatory autoimmune diseases, impacting the small intestine and colon. Clinical symptoms include abdominal pain, diarrhea, intestinal bleeding, fecal urgency and weight loss. Serious complications such as bowel obstruction, colon cancer, malnutrition and abscesses can also occur, resulting in hospitalization and the possible surgical removal of portions of the bowel and colon. Eight hundred and ninety five patients were part of the ulcerative colitis trial conducted in 34 countries, and 1,115 patients were part of the Crohns disease clinical trial conducted in 39 countries. read the article http://newswise.com/articles/potential-new-drug-for-inflammatory-bowel-disease