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Conclusions:? In-hospital VTE risk is higher following gynaecological surgery for malignancy than for benign disease, despite the use of thromboprophylaxis. Given the higher non fatal PE rate after discharge and increasing trend towards shorter hospital LOS, extended prophylaxis in these patients should be considered. ""Background:? Many misoprostol regimens have been used to treat early pregnancy loss as an alternative to surgical evacuation, with differing adverse event and success rates. Aims:? http://www.selleck.cn/products/r428.html This study sought to compare the effectiveness and adverse effects of 800 and 600?��g of misoprostol administered vaginally for the treatment of early pregnancy failure in an outpatient setting. Methods:? A retrospective, observational study of 946 women with a missed miscarriage http://www.selleckchem.com/products/Everolimus(RAD001).html after a missed miscarriage was effectively induced by both 600 and 800?��g of misoprostol. The overall success of medical treatment with intravaginal misoprostol demonstrates that the treatment is safe in an outpatient setting. ""Background:? The puborectalis muscle is believed to play an important role in anal continence. However, to date, there is very limited evidence to support this hypothesis. Aims:? This study was designed to test for an association between puborectalis trauma and ballooning of the levator hiatus on the one hand and anal incontinence on the other http://www.selleckchem.com/products/PD-0332991.html hand. Methods:? The records of 397 women who had attended a tertiary urogynaecological clinic were reviewed in a retrospective study. The history included questions on faecal urgency, soiling, faecal and flatus incontinence. Examination included puborectalis muscle assessment by palpation and 4D pelvic floor ultrasound. Results:? Mean age on presentation was 54 (19�C89) years. Median vaginal parity was 2 (0�C9). Of 397 women, 89 complained of faecal urgency, 65 of faecal incontinence (FI), 67 of soiling and 91 of flatus incontinence. Seventy-seven patients were diagnosed with puborectalis avulsion, of which 38 were bilateral. Puborectalis avulsion was not associated with FI (P?=?0.