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The use of allergen extracts for diagnostic or therapeutic purposes can trigger urticaria or angioedema in dogs. Most episodes of urticaria or angioedema are acute and are presented as relatively urgent cases. Some potential causes, such as caterpillar-induced angioedema or urticaria, may be particularly common in certain geographical areas. Potential differential diagnoses for angioedema include juvenile cellulitis, infected cellulitis, snake bite, oedema, lymphoedema, and neoplasia. Mild and uncomplicated cases of angioedema showing no other signs can be treated as for urticaria. Urticaria pigmentosa has also been described in dogs, although clinically these cases present with a maculopapular eruption that can progress to plaques, nodules, tumours, and bullae, rather than the multiple wheals that occur in classic urticaria. ""Side-effect http://www.selleckchem.com/products/MK-1775.html concerns impede adherence with inhaled corticosteroids (ICS) and often underlie poor asthma control. We developed a brief http://www.selleckchem.com/products/MS-275.html version (ICQ-S) of the 57-item Inhaled Corticosteroids side-effect Questionnaire (ICQ) to facilitate side-effect monitoring in busy clinics. Part 1: After completion by 482 patients with doctor-diagnosed asthma, each ICQ item underwent item reduction analysis. Part 2: Patients prescribed ICS for asthma completed the ICQ at baseline (BL), ICQ-S at day 14 (D14) and day 28 (D28), and 6-item Asthma Control Questionnaire (ACQ) and Mini Asthma Quality of Life Questionnaire (MiniAQLQ) at BL, D14 and D28. 14-day test�Cretest reliability was assessed by intraclass correlation coefficient (ICC) between ICQ-S scores and internal consistency by Cronbach's alpha (��) coefficient and item-total correlations of ICQ-S. Criterion validity was assessed by correlations (Spearman's rho) between ICQ and ICQ-S total score. Patients reported duration and difficulty of ICQ-S completion at D28. Part 1: The ICQ-S consists of fifteen local/systemic ICS side-effects http://en.wikipedia.org/wiki/Mianserin of similar range to the full ICQ. Part 2: 62 asthma patients (mean ACQ score 0.79?��?SD 0.83) prescribed daily ICS [BDP-equivalent median dose 1000?��g (IQR: 500, 1000)] participated. ICC between ICQ-S scores was 0.90. All item-total correlations were rho ��?0.20. The ICQ-S demonstrated criterion validity, for example, ICQ and ICQ-S were strongly associated (rho?=?0.86). 81% of patients completed the ICQ-S within 5?minutes and 97% found completion ��not difficult��. The ICQ-S is a brief, patient-friendly tool with good reliability and validity, which may be useful for monitoring ICS side-effects in clinical practice. ""Bertelsen RJ, L?drup Carlsen KC, Carlsen K-H. Rhinitis in children: Co-morbidities and phenotypes. Pediatr Allergy Immunol 2010: 21: 612�C622. ? 2010 John Wiley & Sons A/S Rhinitis and its co-morbidities affect quality of life; and in children, little is known.